Endosymbiotic Gene Transfer

Proteins encoded by mitochondrial DNA do not account for all of the proteins found in mitochondria. Endosymbiotic prokaryotes are believed to have relinquished certain genes to the nuclei of their host cells in a process known as endosymbiotic gene transfer. For this reason, mitochondria and chloroplasts now depend on their host's DNA to direct synthesis of most of their components. Gene loss, substitution of nuclear genes, and gene transfer cause reduction in the size of the plastid genome (mtDNA, cpDNA).

Microbiologist Kwang Jeon has demonstrated endosymbiotic gene transfer within endosymbiotic strains of Amoeba proteus (xD) with which he has worked since the 1970s.

(J Eukaryot Microbiol 1997 Sep-Oct;44(5):412-9 Evidence for symbiont-induced alteration of a host's gene expression: irreversible loss of SAM synthetase from Amoeba proteus. Choi JY, Lee TW, Jeon KW, Ahn TI)

Free Full Text Article 2004 : Detailed description xD amoeba experiments

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